Sellars M*, Huh JR*, Day K, Issuree PD, Galan C, Gobeil S, Absher D, Green MR, Littman DR. Regulation of DNA methylation dictates Cd4 gene expression during development of helper and cytotoxic T cells. Nature Immunology. 2015 Jul;16(7):746-54. PubMed PMID: 26030024; PubMed Central PMCID: PMC4474743.
Longman RS, Diehl GE, Victorio D, Huh JR, Galan C, Miraldi E, Swaminath A, Bonneau R, Scherl EJ, Littman DR. CX3CR1+ Mononuclear Phagocytes Support Colitis-Associated Innate Lymphoid Cell Production of IL-22. Journal of Experimental Medicine. 2014 Jul 14. pii: jem.20140678.
Huh JR, Englund EE, Wang H, Huang H, Huang P, Rastinejad F, Inglese J, Austin CP, Johnson RL, Huang W, Littman DR. Identification of Potent and Selective Diphenylpropanamide RORg Inhibitors. ACS Med Chem Lett. 2013 4(1):79-84. PMCID: PMC3770298.
Huh JR, Littman DR. Small molecule inhibitors of RORgt: Targeting Th17 cells and other applications. Eur J Immunol. 2012 42(9):2232-7. PMCID: PMC3609417.
Huh JR, Leung WL, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORgt activity. Nature. 2011 472(7344):486-90. PMCID: PMC3172133.
Huh JR, Foe I, Muro I, Chen CH, Seol JH, Yoo SJ, Guo M, Park JM, Hay BA. The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers. J Biol Chem. 2007 282(3):2056-68. PMID: 17068333
Muro I, Berry DL, Huh JR, Chen CH, Huang H, Yoo SJ, Guo M, Baehrecke EH, Hay BA. The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process. Development. 2006 133(17):3305-15. PMID: 16887831.
Muro I, Berry DL, Huh JR, Chen CH, Huang H, Yoo SJ, Guo M, Baehrecke EH, Hay BA. The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process. Development. 2006 133(17):3305-15. PMID: 16887831.
Yan N, Huh JR, Schirf V, Demeler B, Hay BA, Shi Y. Structure and activation mechanism of the Drosophila initiator caspase Dronc. J Biol Chem. 2006 281(13):8667-74. PMID: 16446367.
Hay BA, Huh JR, Guo M. The genetics of cell death: approaches, insights and opportunities in Drosophila. Nat. Rev. Genetics. 2004 5(12):911-922. PMID: 15573123
Huh JR, Guo M, Hay BA. Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role. Curr Biol. 2004 14(14):1262-6. PMID: 15268856.
Huh JR, Vernooy SY, Yu H, Yan N, Shi Y, Guo M, Hay BA. Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. PLoS Biol. 2004 2(1):E15. PMCID: PMC300883.
Huh JR, Hay BA. Apoptosis: sculpture of a fly’s head. Nature. 2002 418(6901):926-8. PMID: 12198529.
Chai J, Yan N, Huh JR, Wu JW, Li W, Hay BA, Shi Y. Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination. Nat Struct Biol. 2003 10(11):892-8. PMID: 14517550.
Olson MR, Holley CL, Yoo SJ, Huh JR, Hay BA, Kornbluth S. Reaper is regulated by IAP-mediated ubiquitination. J Biol Chem. 2003 278(6):4028-34. PMID: 12446669.
Yoo SJ*, Huh JR*, Muro I, Yu H, Wang L, Wang SL, Feldman RM, Clem RJ, Müller HA, Hay BA. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat Cell Biol. 2002 4(6):416-24. PMID: 12021767.
Dorstyn L, Read S, Cakouros D, Huh JR, Hay BA, Kumar S. The role of cytochrome c in caspase activation in Drosophila melanogaster cells. J Cell Biol. 2002156(6):1089-98. PMCID: PMC2173478.
Huh JR, Park JM, Kim M, Carlson BA, Hatfield DL, Lee BJ. Recruitment of TBP or TFIIB to a promoter proximal position leads to stimulation of RNA polymerase II transcription without activator proteins both in vivo and in vitro. Biochem Biophys Res Commun. 1999 256(1):45-51. PMID: 10066420
Cao Y, Kang HL, Xu X, Wang M, Dho SH, Huh JR, Lee BJ, Kalush F, Bocskai D, Ding Y, Tesmer JG, Lee ME, Jurecic V, Baldini A, Weier HU, Doggett NA, Simon MI, Adams MD, and Kim UJ. A 12-Mb complete coverage BAC contig map in human chromosome 16p13.1-p11.2. Genome Research 1999 9(8), 763-774.